Journal: Clinical & Translational Immunology
Article Title: Primary immunodeficiency‐related genes in neonatal intensive care unit patients with various genetic immune abnormalities: a multicentre study in China
doi: 10.1002/cti2.1266
Figure Lengend Snippet: Summary of steps of patient selection and NGS data analysis used in the study. ES, exome sequencing; JAK‐STAT, Janus kinase (JAK)–signal transducer of activators of transcription (STAT); NGS, next‐generation sequencing; NICU, neonatal intensive care unit; PID, primary immunodeficiency. *The patients with life‐threatening infections are eligible if they have sepsis or sepsis shock, or if they need ventilation support or vasopressor therapy or present organ dysfunction, coupled with suspected infection.
Article Snippet: For ES, the capture probes were those used in GenCap Custom Exome Enrichment Kits (MyGenostics, Beijing, China) or TruSight Rapid Capture Kits (Illumina, Inc., San Diego, CA, USA).
Techniques: Selection, Sequencing, Next-Generation Sequencing, Infection